Dectin-2/CLEC6A 蛋白, Mouse (HEK293, His)

Dectin-2/CLEC6A protein has carbohydrate binding and pattern recognition receptor activities, and is involved in the positive regulation of I-kappaB kinase/NF-kappaB signaling, immune response regulation, and fungal response. It is predicted to reside in membranes, particularly on the outside of the plasma membrane, and it is expressed in a variety of tissues, including bone marrow, embryos, lungs, spleen, and thymus. Dectin-2/CLEC6A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Dectin-2/CLEC6A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Dectin-2/CLEC6A Protein, Mouse (HEK293, His) is 166 a.a., with molecular weight of ~23 kDa.

Dectin-2/CLEC6A 蛋白表现出碳水化合物结合活性和模式识别受体活性，在 I-kappaB 激酶/NF-kappaB 信号传导的正向调节、免疫反应调节和对真菌的反应等多种过程中发挥作用。预计它位于膜中并作为膜的组成部分，特别是质膜的外侧。Dectin-2/CLEC6A 蛋白在骨髓、胚胎、肺、脾和胸腺等组织中表达。它是人类 CLEC6A 基因的直系同源对应物。值得注意的是，Dectin-2/CLEC6A 蛋白在肝脏 E18 (RPKM 6.6)、成人脾脏 (RPKM 5.8) 和 13 个其他组织中表现出偏向表达。

Data is not available.

Mouse

HEK293

C-6*His

NP_064385.1 (I44-L209)

56620  [NCBI]

IMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL

Approximately 23 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.