1. 重组蛋白
  2. Enzymes & Regulators
  3. Isomerases (EC 5)
  4. FKBP7 蛋白, Human (199a.a, HEK293, His)

FKBP7 蛋白, Human (199a.a, HEK293, His)

目录号: HY-P70949
产品使用指南

FKBP7 蛋白是一种肽基脯氨酰顺反异构酶 (PPIase),可显着加速蛋白质折叠,尤其是在蛋白质合成的复杂性中。利用其酶促能力,FKBP7 在协调及时的构象变化以实现正确的蛋白质折叠和成熟方面发挥着至关重要的作用。FKBP7 蛋白, Human (199a.a, HEK293, His) 是重组的 FKBP7 蛋白,由 HEK293 表达,带有 C-6*His 标签。FKBP7 蛋白, Human (199a.a, HEK293, His) 全长 199 个氨基酸,分子量为 25-32 kDa。

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描述

The FKBP7 protein is a peptidyl prolyl cis-trans isomerase (PPIase) that significantly accelerates protein folding, especially in the complexities of protein synthesis. Utilizing its enzymatic abilities, FKBP7 plays a crucial role in coordinating timely conformational changes to achieve correct protein folding and maturation. FKBP7 Protein, Human (199a.a, HEK293, His) is the recombinant human-derived FKBP7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FKBP7 Protein, Human (199a.a, HEK293, His) is 199 a.a., with molecular weight of 25-32 kDa.

研究背景

FKBP7 蛋白是一种肽基脯氨酰顺反异构酶 (PPIase),在加速蛋白质折叠方面发挥着关键作用,特别是在蛋白质合成的复杂过程中。利用其酶活性,FKBP7 有助于动态和及时的构象变化,这对于蛋白质的正确折叠和成熟至关重要。作为 PPIase 家族的一员,FKBP7 擅长催化脯氨酸亚胺肽键的顺反异构化,影响新生或错误折叠多肽的结构动力学。这种功能属性强调了该蛋白质在维持细胞蛋白质稳态方面的重要性,并强调了其对细胞生理学的潜在影响。需要进一步的研究来揭示 FKBP7 在合成过程中积极参与蛋白质折叠的复杂编排的具体分子机制。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q9Y680 (Q24-L222)

基因 ID
蛋白结构
N-term
FKBP7 (Q24-L222)
Accession # Q9Y680
6*His
C-term
同用名
Peptidyl-Prolyl Cis-Trans Isomerase FKBP7; PPIase FKBP7; 23 kDa FK506-Binding Protein; 23 kDa FKBP; FKBP-23; FK506-Binding Protein 7; FKBP-7; Rotamase; FKBP7; FKBP23
氨基酸序列

QRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVYQHDEL

分子量

25-32 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FKBP7 Protein, Human (199a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FKBP7 Protein, Human (199a.a, HEK293, His)
目录号:
HY-P70949
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