HPGDS 蛋白, Human

HPGDS protein is a multifunctional enzyme with bifunctionality, and its C-terminal and N-terminal domains have different activities. The C terminus acts as an epoxide hydrolase, promoting xenobiotic metabolism by degrading harmful epoxides and regulating physiological mediator levels. HPGDS Protein, Human is the recombinant human-derived HPGDS protein, expressed by E. coli , with tag free. The total length of HPGDS Protein, Human is 199 a.a., with molecular weight of ~26.0 kDa.

EPHX2 是一种多功能酶，具有双功能性，其 C 端和 N 端结构域具有不同的活性。C 末端结构域充当环氧化物水解酶，靶向氧化烯烃和氧化芳烃，通过降解潜在有害的环氧化物来促进外源代谢。此外，它还在调节生理介质的稳态水平方面发挥作用。另一方面，N 末端结构域表现出脂质磷酸酶活性，优先选择苏型 9,10-膦酰氧基-羟基-十八烷酸和赤型-9,10-膦酰氧基-羟基-十八烷酸等底物。它还证明了对溶血甘油磷脂的磷酸酶活性，对鞘脂和类异戊二烯磷酸盐的溶血脂具有不同的活性。EPHX2 的多功能功能有助于其参与多种生物过程，反映了其在细胞稳态中的重要性。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

Tag Free

O60760 (M1-L199)

27306  [NCBI]

MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL

Approximately 26.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, pH 7.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.