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Results for "2174-59-6" in MCE Product Catalog:

Cat. No. Product Name Target Research Area
  • HY-N1942
    5-O-Demethylnobiletin

    5-Demethylnobiletin

    5-Lipoxygenase Leukotriene Receptor Inflammation/Immunology Neurological Disease Cancer
    5-O-去甲肾上腺素 5-O-Demethylnobiletin (5-Demethylnobiletin) 5-O-去甲肾上腺素,一种从黄芪中分离出的多甲氧基黄酮,是 5-LOX 的直接抑制剂 (IC50=0.1 μM),不影响 COX-2 的表达。 5-O-Demethylnobiletin (5-Demethylnobiletin) 5-O-去甲肾上腺素具有抗炎活性,抑制大鼠中性粒细胞中白三烯 B (4)(LTB4) 的形成和人嗜中性粒细胞中弹性蛋白酶的释放,IC50 值为0.35 μM. 5-O-Demethylnobiletin (5-Demethylnobiletin) 5-O-去甲肾上腺素通过激活 MAPK/ERK-,PKC- 和 PKA 依赖性信号传导途径促进神经发生。