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Results for "Af9 抑制剂" in MCE Product Catalog:

2

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Area
  • HY-112804
    SGC-iMLLT

    Epigenetic Reader Domain Cancer
    SGC-iMLLT 是一种领先的化学探针,也是一种有效选择性的 MLLT1/3-histone 互作抑制剂IC50 值为 0.26 μM。SGC-iMLLT 对 MLLT1 YEATS 域 (YD) 和 MLLT3 YD (AF9/YEATS3) 具有高结合力,Kd 值分别为 0.129 和 0.077 μM。
  • HY-P2266
    SAH-EZH2

    Histone Methyltransferase
    SAH-EZH2 is an EZH2/EPP interaction inhibitor (Kd = 320 nM). SAH-EZH2 suppresses EZH2 expression and H3K27 trimethylation by PCR2 complex. SAH-EZH2 arrests proliferation and induces monocyte to macrophage differentiation of MLL-AF9 leukemia cell line.