2. Metabolic Enzyme/Protease
  3. Aldehyde Dehydrogenase (ALDH)
  4. IGUANA-1 free base

IGUANA-1 free base  (Synonyms: STL5-T-0057)

目录号: HY-148243
产品使用指南

摩尔计算器

IGUANA-1 free base (STL5-T-0057) 是 ALDH1 B1 的选择性抑制剂，IC50 值为 30 nM。IGUANA-1 free base 抑制 SW480 细胞生长在附着或球形条件下，IC50 值分别为 2.46 和 0.39 μM。IGUANA-1 free base 可用于癌症的研究。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 IGUANA-1 通常具有更好的水溶性和稳定性。

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IGUANA-1 free base Chemical Structure

IGUANA-1 free base Chemical Structure

CAS No. : 2756014-24-9

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IGUANA-1 free base 的其他形式现货产品:

Customer Review

Other Forms of IGUANA-1 free base:

IGUANA-1 free base 相关抗体

Top Publications Citing Use of Products

查看 Aldehyde Dehydrogenase (ALDH) 亚型特异性产品:

查看所有亚型
ALDH1 ALDH2 ALDH3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

IGUANA-1 free base (STL5-T-0057) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research of cancer[1].

IC50 & Target

IC50: 30 nM (ALDH1 B1), 2.46 μM (SW480, adherent), 0.39 μM (SW480, spheroid)[1]
体外研究
(In Vitro)

IGUANA-1 free base (compound 68) (0-10 μM) inhibits ALDH1 B1 with an IC50 value of 30 nM[1].
IGUANA-1 free base (0.01-10 μM; 4-5 d) inhibits cell growth of HEK293T cells[1].
IGUANA-1 free base (0.01-10 μM) inhibits cell viability of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IGUANA-1 free base 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HEK293T cell line
Concentration: 0.01-10 μM
Incubation Time: 4-5 d
Result: Showed cell cytotoxicity to HEK293T cells with a GI50 value of 1.7 μM.
分子量

445.94

Formula

C26H24ClN3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

IGUANA-1 free base 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IGUANA-12756014-24-9STL5-T-0057IGUANA1IGUANA 1Aldehyde Dehydrogenase (ALDH)selectiveSW480HEK293TcanceradherentspheroidInhibitorinhibitorinhibit

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目录号：
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