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WJ460 

目录号: HY-124632
产品使用指南

WJ460 是一种有效的肌成纤维蛋白 (MYOF) 抑制剂,可与 MYOF 直接相互作用,并在乳腺癌细胞的纳摩尔范围内发挥抗转移活性。

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WJ460 Chemical Structure

WJ460 Chemical Structure

CAS No. : 1415251-36-3

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Description

WJ460 is a potent myoferlin (MYOF) inhibitor, which interacts directly with MYOF and exerts anti-metastatic activity in the nanomolar range in breast cancer cells[1].

IC50 & Target

MYOF[1]

In Vitro

WJ460 blocks breast cancer cell invasion with IC50 values of 43.37 ± 3.42 nM in MDA-MB-231 and 36.40 ± 4.51 nM in BT549 cells. WJ460 treatment remarkably inhibits MDA-MB-231 and BT549 cell invasion through Collagen I in a dose-dependent manner[1].

In Vivo

WJ460 inhibits breast tumor growth, angiogenesis, and spontaneous metastasis in a spontaneous metastasis model[1].

Molecular Weight

460.59

Formula

C₂₇H₂₈N₂O₃S

CAS No.

1415251-36-3

SMILES

O=C(NCCCCC1=CC=CC=C1)C2=CC=CC(C(N3C4=CC=CC=C4OC)SCC3=O)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
WJ460
目录号:
HY-124632
需求量:

WJ460

Cat. No.: HY-124632