Xanthopterin  (Synonyms: 黄蝶呤)

Xanthopterin, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm^[2]. Xanthopterin (XPT) causes renal growth and hypertrophy in rat^[1]. Xanthopterin inhibits RNA synthesis^[4].

Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC₅₀=109 mM)^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

179.14

C₆H₅N₅O₂

119-44-8

固体

Light yellow to brown

黄蝶呤

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Xanthopterin (XPT), an unconjugated pteridine compound, affects cell growth and differentiation. When injected into rats, XPT has caused changes that have been interpreted as renal growth and hypertrophy.  [Content Brief]

  [2]. Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer Lett. 2005 May 10;222(1):119-24.  [Content Brief]

  [3]. Plotkin M, et al. Xanthopterin in the Oriental hornet (Vespa orientalis): light absorbance is increased with maturation of yellow pigment granules. Photochem Photobiol. 2009 Jul-Aug;85(4):955-61.  [Content Brief]

  [4]. Ziegler I, et al. Pterins and the regulation of lymphocyte activation on the mode of xanthopterin action. Hoppe Seylers Z Physiol Chem. 1984 Jun;365(6):667-73.  [Content Brief]