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  2. Reference Standards Na+/K+ ATPase Mitochondrial Metabolism Reactive Oxygen Species (ROS)
  3. 3-Methylglutaric acid (Standard)

3-Methylglutaric acid (Standard)  (Synonyms: 3-甲基戊二酸 (Standard))

目录号: HY-113410R 纯度: ≥98%
产品使用指南 技术支持

3-Methylglutaric acid (Standard) 是 3-Methylglutaric acid (HY-113410) 的分析标准品。本产品用于研究及分析应用。3-Methylglutaric acid 是一种非选择性线粒体功能抑制剂及 Na+, K+-ATP 酶抑制剂,对大鼠脑皮层突触体 Na+, K+-ATP 酶的抑制率达 30%。3-Methylglutaric acid 能诱导活性氧 (ROS) 生成,从而引发氧化损伤,抑制线粒体氧化还原电位和细胞膜的离子泵功能。3-Methylglutaric acid 可用于研究代谢性疾病的神经病理机制,及氧化应激介导的神经元损伤在神经退行性病变中的作用。

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3-Methylglutaric acid (Standard) Chemical Structure

3-Methylglutaric acid (Standard) Chemical Structure

CAS No. : 626-51-7

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规格 价格 是否有货 数量
25 mg ¥360
3 - 5 周
50 mg ¥530
3 - 5 周
100 mg ¥800
3 - 5 周
250 mg ¥1440
3 - 5 周
500 mg   询价  
1 g   询价  

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Customer Review

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生物活性

3-Methylglutaric acid (Standard) is the analytical standard of 3-Methylglutaric acid (HY-113410). This product is intended for research and analytical applications. 3-Methylglutaric acid is a non-selective inhibitor of mitochondrial function and Na+, K+-ATPase, with an inhibition rate of 30% on rat cortical synaptosomal Na+, K+-ATPase. 3-Methylglutaric acid can induce reactive oxygen species (ROS) generation, thereby causing oxidative damage and inhibiting mitochondrial redox potential and ion pump function of cell membranes. 3-Methylglutaric acid can be used to study the neuropathological mechanisms of metabolic diseases and the role of oxidative stress-mediated neuronal damage in neurodegeneration.

分子量

146.14

Formula

C6H10O4

CAS 号
中文名称

3-甲基戊二酸 (Standard)

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
3-Methylglutaric acid (Standard)
目录号:
HY-113410R
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