首页 产品 化合物库 服务 Kit 关于我们 联系我们

信号通路

在线客服 在线询单 如何订购 促销产品 销售网络 定制服务

在线询价

温馨提示:客服在线时为9:00-18:00,
其他时间可发邮件至sales@medchemexpress.cn,我们会尽快回复您。

Survivin

Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. This has been shown by disruption of survivin induction pathways leading to increase in apoptosis and decrease in tumour growth. Survivin expression is highly regulated by the cell cycle and is only expressed in the G2-M phase. Survivin localizes to the mitotic spindle by interaction with tubulin during mitosis and may play a contributing role in regulating mitosis. Survivin is highly expressed in most cancers and associated with chemotherapy resistance, increased tumor recurrence, and shorter patient survival, making antisurvivin therapy an attractive cancer treatment strategy.

Survivin (2)
产品名称 目录号 简述
YM-155 HY-10194

YM155 (Sepantronium bromide)是新型survivin抑制剂,对survivin启动子的IC50为0.54 nM。

YM-155 hydrochloride HY-10194A

YM155盐酸盐是新型survivin抑制剂,对survivin启动子的IC50为0.54 nM。

Tags: Survivin 抑制 | Survivin 蛋白 | Survivin 抑制剂 | Survivin FDA上市药物 | Survivin 和癌症 | Survivin 活性 | Survivin 激活 | Survivin 信号通路 | Survivin 抑制剂筛选 | Survivin 高通量筛选 | Survivin 抑制剂临床 | Survivin 抑制剂药物 | Survivin 抑制剂综述 | Survivin 抑制剂研发 | Survivin 抑制剂供应商 | Survivin 抑制剂分销商

SiteMap

MCE所有的产品和服务只应用于科学研究,我们不提供产品和服务给任何个人。

Copyright © 2013-2014 MedChemexpress All Rights Reserved 沪ICP备15051369号-1