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DAPK

Death-associated protein kinase (DAPk) is the founding member of a newly classified family of Ser/Thr kinases, whose members not only possess significant homology in their catalytic domains, but also share cell death-associated functions. The realization that DAPk is a tumor suppressor gene, whose expression is lost in multiple tumor types, has spurred a flurry of interest in the kinase family and produced an impressive body of literature concerning its function, regulation, and connection to disease. The DAPk family has been linked to several cell death-related signaling pathways, and functions other than cell death have also been proposed.

Death-associated protein kinase (1)
产品名称 目录号 简述
TC-DAPK 6 HY-15513

TC-DAPK 6 是一种有效的ATP竞争性的选择性 DAPK 抑制剂,作用于 DAPK1DAPK3IC50 分别为 69 和 225 nM。

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