1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Kinesin

Kinesin

Kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule filaments, and are powered by the hydrolysis of ATP (thus kinesins are ATPases). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo. Most kinesins walk towards the plus end of a microtubule, entails transporting cargo from the centre of the cell towards the periphery. Kinesins were discovered as microtubule (MT)-based anterograde intracellular transport motors. The founding member of this superfamily, the genomes of mammals encode more than 40 kinesin proteins, organized into at least 14 families named kinesin-1 through kinesin-14.

Kinesin Isoform Specific Products:

  • Kinesin-5/Eg5/KSP

  • Kinesin-6

  • Kinesin-7/CENP-E

  • Kinesin-12

  • Kinesin-14

Kinesin 相关产品 (16):

Cat. No. Product Name Effect Purity
  • HY-15187
    ARRY-520 Inhibitor 99.41%
    ARRY-520 是一种合成的纺锤体驱动蛋白 (KSP) 抑制剂,IC50 值为 6 nM。
  • HY-15948
    Kif15-IN-1 Inhibitor 99.04%
    Kif15-IN-1 是一种驱动蛋白 Kif15 的抑制剂,主要用于细胞增殖性疾病的研究。
  • HY-50759
    Ispinesib Inhibitor 98.40%
    Ispinesib 是一种特异性的 KSP 抑制剂,Ki app 值为 1.7 nM。
  • HY-10299
    GSK-923295 Inhibitor >99.0%
    GSK-923295 是一种特异性的变构 CENP-E 驱动蛋白 ATPase 活性抑制剂,作用于人类和犬类此酶,Ki 分别为 3.2±0.2 nM 和 1.6±0.1 nM。
  • HY-101071A
    Monastrol Inhibitor 99.89%
    Monastrol是具有高效性和细胞渗透性的有丝分裂驱动蛋白Eg5的抑制剂,IC50值为14 μM.
  • HY-14846
    Litronesib Inhibitor 99.50%
    Litronesib 是一种选择性的 Eg5 抑制剂,具有抗肿瘤的活性。
  • HY-15949
    Kif15-IN-2 Inhibitor
    Kif15-IN-2 是一种驱动蛋白 Kif15 的抑制剂,主要用于细胞增殖性疾病的研究。
  • HY-15857
    CW-069 Inhibitor >98.0%
    CW-069 是一种 HSET 的别构抑制剂,IC50 值为 75 μM。
  • HY-19530
    PF-2771 Inhibitor
    PF-2771 是一种选择性的着丝粒蛋白 E (CENP-E) 抑制剂,IC50 值为 16.1 nM,具有抗肿瘤活性。
  • HY-19966
    K858 Inhibitor 99.76%
    K858 是一种 ATP 非竞争性的 Eg5 抑制剂,IC50 值为 1.3 μM。
  • HY-15187A
    ARRY-520 R enantiomer Inhibitor 98.86%
    ARRY-520 R对映体是ARRY-520的R型,是KSP抑制剂,IC50为6 nM。
  • HY-12069
    SB-743921 Inhibitor
    SB-743921 是一种有效的驱动蛋白 (Eg5) 抑制剂,Ki 值为 0.1 nM。
  • HY-15000
    EMD534085 Inhibitor 98.61%
    EMD534085是有效选择性的有丝分裂驱动蛋白-5 (kinesin-5)的抑制剂,IC50值为8 nM。
  • HY-19944
    Dimethylenastron Inhibitor 98.12%
    Dimethylenastron 是一种有效的 Eg5 抑制剂,IC50 值为 200 nM。
  • HY-14846A
    Litronesib Racemate 99.00%
    Litronesib Racemate 是 litronesib 的外消旋体。Litronesib 是选择性的 Eg5 别构抑制剂。
  • HY-101298
    Paprotrain Inhibitor
    Paprotrain是可渗透细胞的kinesin MKLP-2的抑制剂,抑制 MKLP-2 的 ATPase 活性,IC50 值为 1.35 μM,Ki 值为 3.36 μM,同时对 DYRK1A 有中等的抑制作用,IC50值为 5.5 μM。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.