1. Membrane Transporter/Ion Channel
  2. EAAT2

EAAT2

Excitatory amino acid transporter 2 (EAAT2) is the major glutamate transporter and functions to remove glutamate from synapses. An increase in EAAT2 protein expression and function may provide a means to prevent insufficient glutamate reuptake and consequently reduce neuronal damage.

The glial glutamate transporter EAAT2 plays a major role in glutamate clearance. EAAT2 can be upregulated by transcriptional or translational activation.EAAT2 is a potential target for the prevention of excitotoxicity.

EAAT2 相关产品 (1):

Cat. No. Product Name Effect Purity
  • HY-12741
    LDN-212320 Activator 98.07%
    LDN-212320(OSU-0212320)是谷氨酸转运体EAAT2激动剂,在<5uM浓度下能增强EAAT2水平超过6倍。