1. Anti-infection
  2. HBV

HBV

HBV (Hepatitis B virus), abbreviated HBV, is a species of the genus Orthohepadnavirus, which is likewise a part of the Hepadnaviridae family of viruses. HBV causes the disease hepatitis B. The hepatitis B virus is classified as the type species of the Orthohepadnavirus, which contains three other species: the Ground squirrel hepatitis virus, Woodchuck hepatitis virus, and theWoolly monkey hepatitis B virus. The genus is classified as part of the Hepadnaviridae family. HBV is divided into four major serotypes (adr, adw, ayr, ayw) based on antigenic epitopes present on its envelope proteins, and into eight genotypes (A–H) according to overall nucleotide sequence variation of the genome. The genotypes have a distinct geographical distribution and are used in tracing the evolution and transmission of the virus. Differences between genotypes affect the disease severity, course and likelihood of complications, and response to treatment and possibly vaccination.

HBV 相关产品 (21):

Cat. No. Product Name Effect Purity
  • HY-13782
    Tenofovir Disoproxil Fumarate Inhibitor 99.38%
    Tenofovir Disoproxil Fumarate 是核苷酸逆转录酶抑制剂 (nucleotide reverse transcriptase inhibitor),用于治疗艾滋病和慢性乙型肝炎。
  • HY-100029
    Bay 41-4109 Inhibitor 98.92%
    BAY 41-4109是人乙型肝炎病毒HBV的有效抑制剂,IC50值为53 nM。
  • HY-16468
    Squalamine Inhibitor >98.0%
    Squalamine(MSI-1256)是具有广谱抗病毒活性化的化合物。
  • HY-13986
    Merimepodib Inhibitor 98.22%
    Merimepodib 是次黄嘌呤核苷磷酸脱氢酶 (Inosine monophosphate dehydrogenase) 的非竞争性抑制剂。
  • HY-13623A
    Entecavir monohydrate Inhibitor 99.66%
    Entecavir monohydrate(SQ 34676; BMS 200475)是有选择且有效地HBV抑制剂。在HepG2细胞中的EC50值为3.75 nM。
  • HY-108917
    Morphothiadin Inhibitor 99.59%
    Morphothiadin 是野生型和阿德福韦耐药 HBV 复制的有效抑制剂,其 IC50 值为 12 nM。
  • HY-107902
    RIG-1 modulator 1 Inhibitor 98.81%
    RIG-1 modulator 1 是一种抗病毒化合物,可以用来治疗病毒性感染包括流感病毒,HBV, HCVHIV 来自专利 WO 2015172099 A1。
  • HY-101954
    Inarigivir Inhibitor
    Inarigivir (ORI-9020;SB-9000) 是一种二核苷酸,可显着减少表达乙型肝炎病毒转基因小鼠的 HBV DNA。
  • HY-B0255
    Adefovir dipivoxil Inhibitor 98.50%
    Adefovir Dipivoxil可阻断HBV逆转录酶。
  • HY-13623
    Entecavir Inhibitor 98.88%
    Entecavir(SQ 34676; BMS 200475)是有选择且有效地HBV抑制剂。在HepG2细胞中的EC50值为3.75 nM。
  • HY-100029A
    Bay 41-4109 racemate Inhibitor 98.02%
    BAY 41-4109 racemate是BAY 41-4109的消旋体。BAY 41-4109是人乙型肝炎病毒HBV的有效抑制剂,IC50值为53 nM。
  • HY-13859
    Clevudine Inhibitor >98.0%
    Clevudine能抗乙肝病毒。
  • HY-B0766
    Bicyclol Inhibitor 99.57%
    Bicyclol(SY 801)是可口服的抗HBV,HCV化合物。
  • HY-B0017
    Telbivudine Inhibitor 99.52%
    Telbivudine是特异的HBV复制抑制剂。
  • HY-B2116
    Osalmid Inhibitor 99.80%
    Osalmid是核糖核苷酸还原酶小亚基M2(RRM2)的靶向化合物; 抑制核糖核苷酸还原酶活性的IC50值为8.23 μM。
  • HY-13782A
    Tenofovir Disoproxil Inhibitor >98.0%
    Tenofovir dsoproxil 是核苷酸逆转录酶抑制剂 (nucleotide reverse transcriptase inhibitor),用于治疗艾滋病和慢性乙型肝炎。
  • HY-100029B
    Bay 41-4109 less active enantiomer Inhibitor
    Bay 41-4109 less active enantiomer 是比BAY 41-4109活性低的对应体。BAY 41-4109是人乙型肝炎病毒HBV的有效抑制剂,IC50值为53 nM。
  • HY-B0955
    Oxethazaine Inhibitor 99.86%
    Oxethazaine是一种局部麻醉剂,在防止酸诱导的食管疼痛。
  • HY-16680
    Helioxanthin 8-1 Inhibitor
    Helioxanthin 8-1是helioxanthin类似物,具有抗HBV/HCV/HSV-1/HIV的活性,EC50分别为>5/10/1.4/15 uM。
  • HY-16679
    Helioxanthin derivative 5-4-2 Inhibitor 99.76%
    Helioxanthin derivative 5-4-2是helioxanthin类似物,具有较高的体外抗HBV活性,EC50为0.08 uM。