2. Apoptosis
  3. Apoptosis
  4. 4'-Methoxyflavone

4'-Methoxyflavone 是一种黄酮类化合物，具有抗氧化性和对癌细胞的抗增殖活性。4'-Methoxyflavone 可以抑制细胞周期依赖性激酶导致细胞周期停滞，调节细胞信号传导途径来影响细胞增殖和凋亡。4'-Methoxyflavone 可用于癌症化学预防的研究。

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4'-Methoxyflavone Chemical Structure

4'-Methoxyflavone Chemical Structure

CAS No. : 4143-74-2

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10 mg ￥100
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25 mg ￥200
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4'-Methoxyflavone 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BTI-TN-5B1-4 IC50
27.87 μM
Compound: 3d
Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
[PMID: 20045650]
MCF7 GI50
61.8 μM
Compound: 1e
Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
10.1007/s00044-012-0423-1
MDCK CC50
191.8 μM
Compound: 1f
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
[PMID: 31744778]
MDCK EC50
9.36 nM
Compound: 1f
Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
[PMID: 31744778]
MOLT-4 GI50
99.2 μM
Compound: 1e
Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
10.1007/s00044-012-0423-1
分子量

252.26

Formula

C16H12O3
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 10 mg/mL (39.64 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.9642 mL 19.8208 mL 39.6416 mL
5 mM 0.7928 mL 3.9642 mL 7.9283 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

4'-Methoxyflavone 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9642 mL 19.8208 mL 39.6416 mL 99.1041 mL
5 mM 0.7928 mL 3.9642 mL 7.9283 mL 19.8208 mL
10 mM 0.3964 mL 1.9821 mL 3.9642 mL 9.9104 mL
15 mM 0.2643 mL 1.3214 mL 2.6428 mL 6.6069 mL
20 mM 0.1982 mL 0.9910 mL 1.9821 mL 4.9552 mL
25 mM 0.1586 mL 0.7928 mL 1.5857 mL 3.9642 mL
30 mM 0.1321 mL 0.6607 mL 1.3214 mL 3.3035 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-Methoxyflavone4143-74-2Apoptosisflavonoidantioxidantanti-proliferationcell cycleInhibitorinhibitorinhibit

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产品名称：
4'-Methoxyflavone
目录号：
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