2. Cell Cycle/DNA Damage Others Metabolic Enzyme/Protease
  3. Nucleoside Antimetabolite/Analog Reference Standards DNA/RNA Synthesis Drug Metabolite
  4. 5'-Deoxy-5-fluorocytidine (Standard)

5'-Deoxy-5-fluorocytidine (Standard)  (Synonyms: 5-Fluoro-5'-deoxycytidine (Standard))

目录号: HY-W009538R 纯度: ≥98%
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5'-Deoxy-5-fluorocytidine (Standard)是 5'-Deoxy-5-fluorocytidine (HY-W009538) 的分析标准品。本产品用于研究及分析应用。5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) 是胞苷类似物，Capecitabine (HY-B0016) 的代谢产物。5'-Deoxy-5-fluorocytidine 由 Capecitabine 在肝脏中经羧酸酯酶转化而成。5'-Deoxy-5-fluorocytidine 经胞苷脱氨酶 (cytidine deaminase) 脱氨生成 5'-deoxy-5-fluorouridine，最终在肿瘤组织中经胸苷磷酸化酶转化为 5-fluorouracil (HY-90006)，发挥抗肿瘤作用。5'-Deoxy-5-fluorocytidine 用于结直肠癌、非小细胞肺癌、乳腺癌等实体肿瘤的研究。

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5'-Deoxy-5-fluorocytidine (Standard) Chemical Structure

5'-Deoxy-5-fluorocytidine (Standard) Chemical Structure

CAS No. : 66335-38-4

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规格 价格 是否有货 数量
10 mg ￥250
3 - 5 周
25 mg ￥440
3 - 5 周
50 mg ￥660
3 - 5 周
100 mg ￥1000
3 - 5 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

5'-Deoxy-5-fluorocytidine (Standard) is the analytical standard of 5'-Deoxy-5-fluorocytidine (HY-W009538). This product is intended for research and analytical applications. 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer.

分子量

245.21

同用名

5-Fluoro-5'-deoxycytidine (Standard)

Formula

C9H12FN3O4
CAS 号
中文名称

5-F-5'-脱氧胞苷 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

5'-Deoxy-5-fluorocytidine (Standard) 相关分类

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Keywords:

5'-Deoxy-5-fluorocytidine (Standard)66335-38-45-Fluoro-5'-deoxycytidine (Standard)5-F-5'-脱氧胞苷 (Standard)Nucleoside Antimetabolite/AnalogReference StandardsDNA/RNA SynthesisDrug MetaboliteDNA methyltransferasesanti-metabolicanti-tumorInhibitorinhibitorinhibit

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