2. Membrane Transporter/Ion Channel Neuronal Signaling Vitamin D Related/Nuclear Receptor
  3. GABA Receptor Constitutive Androstane Receptor
  4. 5α-Androstan-3α-ol

5α-Androstan-3α-ol  (Synonyms: 3α,5α-Androstanol)

目录号: HY-W722556
产品使用指南 技术支持

5α-Androstan-3α-ol 是一种γ-氨基丁酸 (GABA) 受体激动剂。5α-Androstan-3α-ol 能够抑制孤儿核受体 CAR (组成型雄烷受体) 的转录活性。5α-Androstan-3α-ol 通过结合 CAR 并促进其与共激活蛋白解离，从而负调控 CAR 的活性。5α-Androstan-3α-ol 可用于研究核受体介导的激素代谢和药物解毒机制。

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5α-Androstan-3α-ol Chemical Structure

5α-Androstan-3α-ol Chemical Structure

CAS No. : 7657-50-3

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5α-Androstan-3α-ol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5α-Androstan-3α-ol is a γ-aminobutyric acid (GABA) receptor agonist. 5α-Androstan-3α-ol can inhibit the transcriptional activity of the orphan nuclear receptor CAR (constitutive androstane receptor). 5α-Androstan-3α-ol negatively regulates the activity of CAR by binding to CAR and promoting its dissociation from coactivator proteins. 5α-Androstan-3α-ol can be used to study nuclear receptor-mediated hormone metabolism and drug detoxification mechanisms[1].

分子量

276.46

Formula

C19H32O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5α-Androstan-3α-ol 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5α-Androstan-3α-ol7657-50-33α,5α-AndrostanolGABA ReceptorConstitutive Androstane ReceptorGamma-aminobutyric acid Receptorγ-Aminobutyric acid ReceptorCARNR1I3Nuclear receptorsDNAGABAInhibitorinhibitorinhibit

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