1. Cell Cycle/DNA Damage
    Epigenetics
  2. HDAC

ACY-957 

目录号: HY-104008
产品使用指南

ACY-957 是一种选择性的 HDAC1HDAC2 抑制剂,对 HDAC1/2/3 的 IC50 值分别为 7 nM,18 nM 和 1300 nM,对 HDAC4/5/6/7/8/9 无作用。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

ACY-957 Chemical Structure

ACY-957 Chemical Structure

CAS No. : 1609389-52-7

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 实验参考方法

  • 技术信息

  • 纯度 & 产品资料

  • 参考文献

Description

ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9.

IC50 & Target[1]

HDAC1

7 nM (IC50)

HDAC2

18 nM (IC50)

HDAC3

1300 nM (IC50)

In Vitro

ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC50 of 304 nM for HDAC2 in primary hematopoietic progenitors[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3281 mL 11.6404 mL 23.2807 mL
5 mM 0.4656 mL 2.3281 mL 4.6561 mL
10 mM 0.2328 mL 1.1640 mL 2.3281 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

429.54

Formula

C₂₄H₂₃N₅OS

CAS No.

1609389-52-7

SMILES

O=C(C1=CC=C2N=C(N3CCNCC3)C=CC2=C1)NC4=CC(C5=CC=CS5)=CC=C4N

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
ACY-957
目录号:
HY-104008
需求量:

ACY-957

Cat. No.: HY-104008