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BLM-IN-1 

目录号: HY-111756
产品使用指南

BLM-IN-1 (compound 29) 是有效的、布鲁姆综合征蛋白 (BLM) 的抑制剂,对BLM的KD 值为1.81 μM,IC50 值为0.95 μM。可诱导DNA损伤反应,癌细胞的凋亡和增殖抑制。

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BLM-IN-1 Chemical Structure

BLM-IN-1 Chemical Structure

CAS No. : 2056014-40-3

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Description

BLM-IN-1 (compound 29) is an effective Bloom syndrome protein (BLM) inhibitor, with a strong BLM binding KD of 1.81 μM and an IC50 of 0.95 μM for BLM. Induces DNA damage response, as well as apoptosis and proliferation arrest in cancer cells[1].

IC50 & Target

IC50: 1.95 μM (BLM)[1].

References
Molecular Weight

462.60

Formula

C₂₈H₃₅FN₄O

CAS No.

2056014-40-3

SMILES

CCN(CC)CCCNC1=CC(N=C(/C(CC2)=C/C3=CC=C(C(C)C)C=C3)N2C4=O)=C4C=C1F

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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产品名称:
BLM-IN-1
目录号:
HY-111756
需求量:

BLM-IN-1

Cat. No.: HY-111756