1. Metabolic Enzyme/Protease
    Anti-infection
  2. HIV Integrase
    HIV

HIV-1 integrase inhibitor 4 

目录号: HY-108820
产品使用指南

HIV-1 integrase inhibitor 4 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 3.7 nM。

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HIV-1 integrase inhibitor 4 Chemical Structure

HIV-1 integrase inhibitor 4 Chemical Structure

CAS No. : 1638504-66-1

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10 mg ¥7500 Get quote

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Description

HIV-1 integrase inhibitor 4 is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM.

IC50 & Target

IC50: 3.7 nM (INST)[1]

In Vitro

HIV-1 integrase inhibitor 4 (compound 4f) is a HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. HIV-1 integrase inhibitor 4 shows potent activity against recombinant HIV IN in biochemical assays and good efficacy in assays done in cell culture against a broad panel of viral mutants carrying the major RAL and DTG IN resistance mutations[1].

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.9436 mL 9.7182 mL 19.4363 mL
5 mM 0.3887 mL 1.9436 mL 3.8873 mL
10 mM 0.1944 mL 0.9718 mL 1.9436 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

514.5

Formula

C₂₄H₂₀F₂N₄O₅S

CAS No.

1638504-66-1

SMILES

NC(C1=CC(CCS(=O)(C2=CC=CC=C2)=O)=CN=C1N3O)=C(C(NCC4=CC=C(F)C=C4F)=O)C3=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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产品名称:
HIV-1 integrase inhibitor 4
目录号:
HY-108820
需求量: