1. GPCR/G Protein
  2. Adenosine Receptor

MethADP (Synonyms: Adenosine 5'-(α,β-methylene)diphosphate)

目录号: HY-112502
产品使用指南

MethADP 是一个特异性的 CD73 抑制剂。

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MethADP Chemical Structure

MethADP Chemical Structure

CAS No. : 3768-14-7

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Description

MethADP is a specific CD73 inhibitor.

IC50 & Target

CD73[1].

In Vitro

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3517 mL 11.7583 mL 23.5167 mL
5 mM 0.4703 mL 2.3517 mL 4.7033 mL
10 mM 0.2352 mL 1.1758 mL 2.3517 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

425.23

Formula

C₁₁H₁₇N₅O₉P₂

CAS No.

3768-14-7

SMILES

O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3COP(O)(CP(O)(O)=O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
MethADP
目录号:
HY-112502
需求量:

MethADP

Cat. No.: HY-112502