1. Cell Cycle/DNA Damage
    Epigenetics
  2. Sirtuin
  3. Sirt2-IN-1

Sirt2-IN-1 

目录号: HY-112427
产品使用指南

Sirt2-IN-1 (Compound 9) 是一种 sirtuin 2 (Sirt2) 抑制剂,IC50 为 163 nM。

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Sirt2-IN-1 Chemical Structure

Sirt2-IN-1 Chemical Structure

CAS No. : 1862238-00-3

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥6748 In-stock
5 mg ¥5500 In-stock
10 mg ¥8500 In-stock
50 mg ¥26500 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

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Description

Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1].

IC50 & Target[1]

SIRT2

163 nM (IC50)

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (268.97 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7931 mL 8.9656 mL 17.9311 mL
5 mM 0.3586 mL 1.7931 mL 3.5862 mL
10 mM 0.1793 mL 0.8966 mL 1.7931 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
In Vivo:
  • 1.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (4.48 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
Molecular Weight

557.69

Formula

C₂₈H₂₇N₇O₂S₂

CAS No.

1862238-00-3

SMILES

O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Sirt2-IN-1
目录号:
HY-112427
需求量:

Sirt2-IN-1

Cat. No.: HY-112427