1. Metabolic Enzyme/Protease
  2. Aldose Reductase

Aldose Reductase

Aldose reductase is an NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides. It is primarily known for catalyzing the reduction of glucose to sorbitol, the first step in polyol pathway of glucose metabolism. The aldose reductase reaction, in particular the sorbitol produced, is important for the function of various organs in the body. Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes.

Aldose Reductase 相关产品 (9):

Cat. No. Product Name Effect Purity
  • HY-N0102
    Isoliquiritigenin Inhibitor
    Isoliquiritigenin 是从光果甘草根中分到的黄酮类化合物,具有抗肿瘤的活性,能够抑制 aldose reductase 的活性,IC50 值为 320 nM。
  • HY-66009
    Epalrestat Inhibitor 99.46%
    Epalrestat是醛糖还原酶抑制剂,可作用于糖尿病神经病变。
  • HY-15314
    Ranirestat Inhibitor 99.14%
    Ranirestat (AS-3201)是醛糖还原酶抑制剂,糖尿病性神经病变临床3期。
  • HY-16500
    Tolrestat Inhibitor
    Tolrestat 是一种有效的,可口服的 aldose reductase 抑制剂,IC50 值为 35 nM。
  • HY-18967
    Aldose reductase-IN-1 Inhibitor 99.72%
    Aldose reductase-IN-1是一种醛糖还原酶抑制剂, IC50值为28.9 pM。
  • HY-B1202
    Alrestatin Inhibitor
    Alrestatin是醛糖还原酶抑制剂, 醛糖还原酶是涉及糖尿病并发症发病机制的一种酶, 包括糖尿病性神经病。
  • HY-16433
    RISARESTAT Inhibitor
    RISARESTAT (CT-112)是一种醛糖还原酶抑制剂,开发用于治疗糖尿病并发症。
  • HY-16255
    IMIRESTAT Inhibitor
    IMIRESTAT 是一种 aldose reductase 抑制剂,可用于治疗糖尿病。
  • HY-B1202A
    Alrestatin sodium Inhibitor
    Alrestatin钠是醛糖还原酶抑制剂, 醛糖还原酶是涉及糖尿病并发症发病机制的一种酶, 包括糖尿病性神经病。