1. Cytoskeleton
  2. Gap Junction Protein

Gap Junction Protein

Gap junction channels are essential in normal heart function and they assist in the mediated spread of electrical impulses that stimulate synchronized contraction (via an electrical syncytium) of cardiac tissues.

Gap junction (GJ) proteins play an important role in direct communication between cells of many tissue types. GJs are specialised intercellular membrane-spanning domains that allow the passage of small molecules including second messenger (e.g. c-AMP, inositol triphosphate) or ionic signals from one cell to another. GJ proteins and their long evolutionary history have permitted adaptation of gap junction intercellular communication (GJIC) with several important functions and multiple regulatory processes. Formation of GJIC is an essential mechanism in coordinating growth and development and tissue compartmentalization during embryonic development.

Gap Junction Protein 相关产品 (5):

Cat. No. Product Name Effect Purity
  • HY-15204
    Tonabersat Modulator 98.48%
    Tonabersat 是一种 gap-junction 调节剂。
  • HY-10913A
    GAP-134 Hydrochloride Modulator 99.20%
    GAP-134(Danegaptide, ZP 1609)盐酸盐为修饰的二肽,是第二代口服生物相容性的缝隙连接调节剂。
  • HY-P0139
    Gap 27 Inhibitor 98.34%
    Gap 27,connexin43拟肽,是间隙连接抑制剂。
  • HY-10913
    GAP-134 Modulator
    GAP-134 (Danegaptide, ZP 1609)是修饰的二肽,是第二代口服生物相容性的间隙连接调节剂。
  • HY-P1082
    Gap 26 Inhibitor 99.30%
    Gap 26 是一种连接蛋白 (connexin) 模拟肽,与 connexin 43 的 63-75 位氨基酸残基相对应,为 gap junction 的阻滞剂。
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