1. Signaling Pathways
  2. GPCR/G Protein
  3. Motilin Receptor

Motilin Receptor

Motilin receptor is a G protein-coupled receptor that binds motilin. Motilin in turn is an intestinal peptide that stimulates contraction of gutsmooth muscle. The main function of motilin is to increase the migrating myoelectric complex component of gastrointestinal motility and stimulate the production of pepsin. Motilin is called "housekeeper of the gut" because it improves peristalsis in the small intestine and clears out the gut to prepare for the next meal. A high level of motilin secreted between meals into the blood stimulates the contraction of the fundus and antrum and accelerates gastric emptying. It then contracts the gallbladder and increases the squeeze pressure of the lower esophageal sphincter. Other functions of motilin include increasing the release of pancreatic polypeptide and somatostatin.

Motilin Receptor 相关产品 (3):

Cat. No. Product Name Effect Purity
  • HY-10922
    Camicinal Agonist
    Camicinal (GSK962040) 是胃动素受体激动剂,pEC50为7.9。
  • HY-P1037
    Motilin (26-47), human, porcine Agonist
    Motilin (26-47), human, porcine 是一种内源性的 motilin 受体激动剂,在中国仓鼠卵巢细胞中,Ki 值和 EC50 值分别为 2.3 nM 和 0.3 nM。
  • HY-10922A
    Camicinal hydrochloride Agonist
    Camicinal (GSK962040) 盐酸盐是胃动素受体激动剂,pEC50为7.9。
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