1. Signaling Pathways
  2. GPCR/G Protein
  3. Neurotensin Receptor

Neurotensin Receptor

Neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene. Neurotensin (NTS) is a 13-amino-acid peptide that functions as both a neurotransmitter and a hormone through the activation of the neurotensin receptor NTSR1, a G-protein-coupled receptor (GPCR). In the brain, NTS modulates the activity of dopaminergic systems, opioid-independent analgesia, and the inhibition of food intake; in the gut, NTS regulates a range of digestive processes.

Neurotensin Receptor 相关产品 (3):

Cat. No. Product Name Effect Purity
  • HY-P0234
    Neurotensin Agonist
    Neurotensin 是一种肠十三肽,作为有效的细胞有丝分裂原,作用于各种结肠直肠癌和胰腺癌,对神经降压素受体 (neurotensin receptorNTR) 具有高亲和力。
  • HY-16639
    ML314 Agonist 99.72%
    ML314是NTR1激动剂,EC50为1.9 μM,对NTR2和GPR35抑制性较弱,不能刺激钙离子转移。
  • HY-P1255
    Kinetensin Agonist
    Kinetensin是从胃蛋白酶处理的人血浆分离的神经降压素 (neurotensin-like) 样肽。
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