1. Signaling Pathways
  2. CD44

CD44 

In (Lu)-related protein p80; Pgp-1/Ly-24; ECMRIII; HUTCH-1

CD44 是一种非激酶细胞表面跨膜糖蛋白。它被克隆并归类为软骨连接蛋白家族成员。CD44 被认为是透明质酸的主要细胞表面受体,透明质酸是主要的细胞外基质 (ECM) 成分。CD44 在淋巴细胞、平滑肌、成纤维细胞和各种类型的上皮中显著表达,并参与淋巴细胞归巢、细胞粘附和聚集、细胞迁移、白细胞活化、淋巴细胞生成和骨髓生成、血管生成和细胞因子释放。

CD44 is a non-kinase cell surface transmembrane glycoprotein. It was cloned and classified as a member of the cartilage junction protein family. CD44 is considered to be the major cell surface receptor for hyaluronan, a major extracellular matrix (ECM) component. CD44 is prominently expressed on lymphocytes, smooth muscle, fibroblasts, and various types of epithelium and is involved in lymphocyte homing, cell adhesion and aggregation, cell migration, leukocyte activation, lymphopoiesis and myelopoiesis, angiogenesis, and cytokine release.

CD44 相关产品 (0):

Cat. No. Product Name Effect Purity Chemical Structure