2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Emopamil Binding Protein

Emopamil Binding Protein (Emopamil 结合蛋白)

Emopamil Binding Protein

Emopamil Binding Protein (EBP) 是一种膜结合的胆固醇生物合成酶，参与胆固醇合成的关键步骤，并且是神经保护剂的靶标，属于扩展的 EBP 超家族。Emopamil Binding Protein 主要在内质网膜定位并广泛表达于多种组织中，尤其是肝脏。EBP 可结合化疗药物降低其有效性导致肿瘤耐药性。

Emopamil Binding Protein (EBP) is a membrane-bound cholesterol biosynthetic enzyme involved in the key steps of cholesterol synthesis and a target for neuroprotective agents. It belongs to the extended EBP superfamily. Emopamil Binding Protein is mainly localized in the endoplasmic reticulum membrane and widely expressed in various tissues, especially the liver. EBP can bind to chemotherapeutic drugs, reducing their effectiveness and leading to tumor resistance.

Emopamil Binding Protein 相关产品 (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-162351
    EBP-IN-1 Inhibitor 99.67%
    EBP-IN-1 (compound 11) 是 emopamil 结合蛋白 (EBP) 的抑制剂，而 EBP 是胆固醇生物合成途径中的一种甾醇异构酶。EBP-IN-1 在啮齿类动物中的半衰期较长，具有良好的代谢周转和脑渗透特性。EBP-IN-1 增强了人类皮质类器官中少突胶质细胞的形成。
    EBP-IN-1
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