Small Interfering RNA (siRNA) (小干扰RNA)

小分子干扰RNA（siRNA）是一种小的外源性双链RNA（dsRNA）（20-25个核苷酸），可启动RNA干扰（RNAi）途径。短的dsRNA解旋，正链降解，反链与多种蛋白质成分形成RNA诱导沉默复合物（RISC）。RISC中保留的反义链与靶基因mRNA特异性互补。同时，RISC具有核酸酶活性，可以切割和降解靶基因mRNA，抑制靶基因的表达。不完全互补导致mRNA翻译抑制。

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) 相关产品 (29528):

By Effects:	Pre-designed Sets (29143) 抑制剂 (10) 降解剂 (1) 诱导剂 (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-RS14004

Sucnr1 Mouse Pre-designed siRNA Set A	Pre-designed Sets
Sucnr1 Mouse Pre-designed siRNA Set A 包括针对 Sucnr1 (Mouse) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

Sucnr1 Mouse Pre-designed siRNA Set A Sucnr1 Mouse Pre-designed siRNA Set A

HY-RS13325

SLC7A11 Human Pre-designed siRNA Set A	Pre-designed Sets
SLC7A11 Human Pre-designed siRNA Set A 包括针对 SLC7A11 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

SLC7A11 Human Pre-designed siRNA Set A SLC7A11 Human Pre-designed siRNA Set A

HY-147266

Elebsiran sodium
Elebsiran sodium 是一种抗乙型肝炎病毒 (HBV) 和丁型肝炎病毒 (HDV) 感染的 siRNA。

HY-RS06168

HIF1A Human Pre-designed siRNA Set A	Pre-designed Sets
HIF1A Human Pre-designed siRNA Set A 包括针对 HIF1A (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

HIF1A Human Pre-designed siRNA Set A HIF1A Human Pre-designed siRNA Set A

HY-RS05189

G3BP1 Human Pre-designed siRNA Set A	Pre-designed Sets
G3BP1 Human Pre-designed siRNA Set A 包括针对 G3BP1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

G3BP1 Human Pre-designed siRNA Set A G3BP1 Human Pre-designed siRNA Set A

HY-P990053

Nelistotug
Nelistotug (GSK 6097608; GSK6097608) 是靶向 CD96 的人源 IgG1κ 抗体。CD96 是免疫球蛋白超家族成员，是潜在的免疫检查点。

HY-RS16219

SPP1 Mouse Pre-designed siRNA Set A	Pre-designed Sets
SPP1 Mouse Pre-designed siRNA Set A 包括针对 SPP1 (Mouse) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

SPP1 Mouse Pre-designed siRNA Set A SPP1 Mouse Pre-designed siRNA Set A

HY-RS05857

GSDMD Human Pre-designed siRNA Set A	Pre-designed Sets
GSDMD Human Pre-designed siRNA Set A 包括针对 GSDMD (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

GSDMD Human Pre-designed siRNA Set A GSDMD Human Pre-designed siRNA Set A

HY-RS15911

YAP1 Human Pre-designed siRNA Set A	Pre-designed Sets
YAP1 Human Pre-designed siRNA Set A 包括针对 YAP1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

YAP1 Human Pre-designed siRNA Set A YAP1 Human Pre-designed siRNA Set A

HY-RS01129

ATF3 Human Pre-designed siRNA Set A	Pre-designed Sets
ATF3 Human Pre-designed siRNA Set A 包括针对 ATF3 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

ATF3 Human Pre-designed siRNA Set A ATF3 Human Pre-designed siRNA Set A

HY-RS08355

METTL14 Human Pre-designed siRNA Set A	Pre-designed Sets
METTL14 Human Pre-designed siRNA Set A 包括针对 METTL14 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

METTL14 Human Pre-designed siRNA Set A METTL14 Human Pre-designed siRNA Set A

HY-RS07572

LDHB Human Pre-designed siRNA Set A	Pre-designed Sets
LDHB Human Pre-designed siRNA Set A 包括针对 LDHB (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

LDHB Human Pre-designed siRNA Set A LDHB Human Pre-designed siRNA Set A

HY-153609

AS-Patisiran sodium
AS-Patisiran sodium 是 Patisiran 的反义链。Patisiran 是一种双链小干扰 RNA，靶向 Transthyretin (TTR) 信使 RNA 内的序列。Patisiran 特异性抑制突变体和野生型 TTR 的肝脏合成。Patisiran 可用于研究遗传性 TTR 淀粉样蛋白症的研究。

HY-RS13886

STAT1 Human Pre-designed siRNA Set A	Pre-designed Sets
STAT1 Human Pre-designed siRNA Set A 包括针对 STAT1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

STAT1 Human Pre-designed siRNA Set A STAT1 Human Pre-designed siRNA Set A

HY-RS12352

RUNX3 Human Pre-designed siRNA Set A	Pre-designed Sets
RUNX3 Human Pre-designed siRNA Set A 包括针对 RUNX3 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

RUNX3 Human Pre-designed siRNA Set A RUNX3 Human Pre-designed siRNA Set A

HY-RS12937

SIRT1 Human Pre-designed siRNA Set A	Pre-designed Sets
SIRT1 Human Pre-designed siRNA Set A 包括针对 SIRT1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

SIRT1 Human Pre-designed siRNA Set A SIRT1 Human Pre-designed siRNA Set A

HY-RS00028

AARS1 Human Pre-designed siRNA Set A	Pre-designed Sets
AARS1 Human Pre-designed siRNA Set A 包括针对 AARS1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

AARS1 Human Pre-designed siRNA Set A AARS1 Human Pre-designed siRNA Set A

HY-RS05069

FOXO1 Human Pre-designed siRNA Set A	Pre-designed Sets
FOXO1 Human Pre-designed siRNA Set A 包括针对 FOXO1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

FOXO1 Human Pre-designed siRNA Set A FOXO1 Human Pre-designed siRNA Set A

HY-RS03597

DCTPP1 Human Pre-designed siRNA Set A	Pre-designed Sets
DCTPP1 Human Pre-designed siRNA Set A 包括针对 DCTPP1 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

DCTPP1 Human Pre-designed siRNA Set A DCTPP1 Human Pre-designed siRNA Set A

HY-RS13591

SOX2 Human Pre-designed siRNA Set A	Pre-designed Sets
SOX2 Human Pre-designed siRNA Set A 包括针对 SOX2 (Human) 基因的不同区域设计三对 siRNA，以及阴性对照、FAM 标记阴性对照和阳性对照。

SOX2 Human Pre-designed siRNA Set A SOX2 Human Pre-designed siRNA Set A

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