2. Neuronal Signaling
  3. Sigma Receptor
  4. AB21 oxalate

AB21 oxalate 是一种有效的选择性 S1R 拮抗剂，对 S1R 和 S2R 的 Ki 分别为 13 nM 和 102 nM。AB21 oxalate 具有降低机械超敏反应的作用。

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AB21 oxalate Chemical Structure

AB21 oxalate Chemical Structure

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Other Forms of AB21 oxalate:

AB21 oxalate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AB21 oxalate is a potent and selective S1R antagonist with Kis of 13, 102 nM for S1R and S2R. AB21 oxalate has the effect of reducing mechanical hypersensitivity[1].

体外研究
(In Vitro)

AB21 oxalate 在 S1R 放射性配体结合测定实验中，有或没有 Phenythoin (HY-B0448) 条件下测得的 Ki 值分别为 12 nM 和 14 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AB21 oxalate 相关抗体:
体内研究
(In Vivo)

AB21 oxalate (20 mg/kg, s.c., 注射 Capsaicin (HY-10448) 前 30 分钟给药) 可逆转 Phenythoin (HY-B0448) 诱导的疼痛模型中的机械性超敏反应，并显示出比 BD1063 dhydrochloride (HY-18101A) 更高的效力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

438.52

Formula

C25H30N2O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AB21 oxalate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AB21AB 21AB-21Sigma ReceptorS1R antagonistCapsaicin-induced mechanical hypersensitivityInhibitorinhibitorinhibit

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产品名称：
AB21 oxalate
目录号：
HY-149854A
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