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Alclometasone dipropionate  (Synonyms: Sch 22219)

目录号: HY-106566
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Alclometasone dipropionate (Sch 22219) 是类固醇化合物。Alclometasone dipropionate 可用于皮炎和皮肤瘙痒的研究。

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Alclometasone dipropionate Chemical Structure

Alclometasone dipropionate Chemical Structure

CAS No. : 66734-13-2

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规格 价格 是否有货 数量
2500 μg ￥1580
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Alclometasone dipropionate 相关抗体

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生物活性

Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch[1][2].

体外研究
(In Vitro)

Alclometasone dipropionate (0.01-100 ng/mL; 24 h) suppresses cytokine production of CD3/CD2 stimulation with IC50s of 5.54, 1.76, 2.09, 0.89, 3.26 and 0.76 ng/mL for IL-2, IL-3, IL-4, IL-5, IFN-γ and GM-CSF, respectively in human PBMC[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Alclometasone dipropionate 相关抗体:
体内研究
(In Vivo)

Alclometasone dipropionate (0.1% (20 μL); both sides of the ears; once) shows effects on tuberculin- and egg albumin-induced allergic reaction[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats with tuberculin-induced delayed allergic reaction[2]
Dosage: 0.1% (20 μL)
Administration: Both sides of the ears; 0.1% (20 μL) 3 h before and 2 h after tuberculin challenge
Result: Partially inhibited the increase in amount of dye leaked.
Animal Model: Brown-Norway rats with egg albumin-induced passive cutaneous anaphylaxis reaction[2]
Dosage: 0.1% (20 μL)
Administration: Both sides of the ears; 0.1% (20 μL) 6 h before egg albumin challenge
Result: Significantly suppressed the increase in amount of dye leaked in this passive cutaneous anaphylaxis reaction.
Clinical Trial
分子量

521.04

Formula

C28H37ClO7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Alclometasone dipropionate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alclometasone66734-13-2Sch 22219Sch22219Sch-22219OtherssteroidcytokinePBMCtuberculinegg albuminallergic reactionInhibitorinhibitorinhibit

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