2. Others GPCR/G Protein
  3. Reference Standards CRFR
  4. Antalarmin hydrochloride (Standard)

Antalarmin hydrochloride (Standard) 

目录号: HY-103377R 纯度: ≥98%
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Antalarmin (hydrochloride) (Standard)是 Antalarmin (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Antalarmin (hydrochloride) 是一种具有口服活性的非肽类促肾上腺皮质激素释放激素受体1 (CRHR1) 拮抗剂，其Ki 为 1 nM。Antalarmin hydrochloride 抑制动物模型中 CRH 诱导的 ACTH 分泌，并阻断 CRH 和新奇感诱导的焦虑样行为。Antalarmin hydrochloride 在关节炎模型中产生抗炎作用，并抑制与肠易激综合征相关的应激性胃溃疡。

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Antalarmin hydrochloride (Standard) Chemical Structure

Antalarmin hydrochloride (Standard) Chemical Structure

CAS No. : 220953-69-5

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生物活性

Antalarmin (hydrochloride) (Standard) is the analytical standard of Antalarmin (hydrochloride). This product is intended for research and analytical applications. Antalarmin (hydrochloride) is an oral active non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.

分子量

415.01

Formula

C24H35ClN4
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Antalarmin hydrochloride (Standard) 相关分类

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Keywords:

Antalarmin hydrochloride (Standard)220953-69-5Reference StandardsCRFRCorticotropin-releasing Factor ReceptorCRHRHMC-1 and hCBMC cellsCRF-induced anxiety-like behavior modelInhibitorinhibitorinhibit

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