2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation GPCR/G Protein Cytoskeleton Cell Cycle/DNA Damage Apoptosis
  3. Antibody-Drug Conjugates (ADCs) CCR Microtubule/Tubulin Apoptosis
  4. Anti-CCL2 (Carlumab)-VcMMAE

Anti-CCL2 (Carlumab)-VcMMAE 是一种抗体-药物偶联物 (ADC)，由人源性抗 CCL2 (趋化因子配体 2) 抗体 Carlumab (HY-P99188) 与 valine-citrulline (vc) 和微管蛋白 (tubulin) 抑制剂 MMAE (HY-15162) 缀合而成。ADC 毒性分子和 linker 部分是 McMMAE (HY-15575) 。Anti-CCL2 (Carlumab)-VcMMAE 可诱导细胞凋亡 (Apoptosis) 并用于癌症的研究。

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Anti-CCL2 (Carlumab)-VcMMAE Chemical Structure

Anti-CCL2 (Carlumab)-VcMMAE Chemical Structure

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     可免费申领三个不同产品的试用装。

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Anti-CCL2 (Carlumab)-VcMMAE 相关抗体

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CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-CCL2 (Carlumab)-VcMMAE is an antibody-drug conjugate (ADC) consisting of the humanized anti-CCL2 (chemokine ligand 2) antibody Carlumab (HY-P99188) conjugated with valine-citrulline (vc) and the tubulin inhibitor MMAE (HY-15162). The ADC toxic molecule and linker part are McMMAE (HY-15575). Anti-CCL2 (Carlumab)-VcMMAE induces apoptosis and can be used in cancer research[1][2].

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-CCL2 (Carlumab)-VcMMAE 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-CCL2 (Carlumab)-VcMMAEAntibody-Drug Conjugates (ADCs)CCRMicrotubule/TubulinApoptosisAntibody-Drug ConjugatesCC chemokine receptorADCanticancerInhibitorinhibitorinhibit

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