2. Anti-infection
  3. Bacterial
  4. Anti-MRSA agent 5

Anti-MRSA agent 5 是一种有效的MRSA拮抗剂，MIC50为0.38 μg/mL，hERG活性较低，其IC50值大于40μM。Anti-MRSA agent 对哺乳动物细胞的毒性也很低，不太可能获得细菌的耐药性。

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Anti-MRSA agent 5 Chemical Structure

Anti-MRSA agent 5 Chemical Structure

CAS No. : 2490154-44-2

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Anti-MRSA agent 5 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-MRSA agent 5 (B14) is a potent
MRSA
agent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance[1].

IC50 & Target

MIC: 0.38 μg/mL (MRSA); IC50: >40 Μm (hERG)
体外研究
(In Vitro)

Anti-MRSA agent 5 (B14) is highly selective toxic in bacterial cells. Anti-MRSA agent has marginal inhibitory activities with an IC50 values of exceeding 40 μM. Anti-MRSA agent 5 (B14) has strong antibacterial activity for all five clinical isolates of MRSA (NRS-1, NRS-70, NRS-100, NRS-108, NRS-271) with MIC values between < 0.17 and 0.69 μg/mL.Anti-MRSA agent 5 (B14) inhibits all three clinical isolates of fluoroquinolone-resistant MRSA (19-25, 19-26, 19-27) and exhibits good potency against VISA[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-MRSA agent 5 相关抗体:

Cell Cytotoxicity Assay

Cell Line: A549, MDA-MB-231, PC-3, ABAE.
Concentration: 0–400 μM
Incubation Time: 48h
Result: Showed marginal inhibitory activities with anIC50 exceeding 40 μM and displayed highly selective toxicity toward bacterial cells.
分子量

442.47

Formula

C25H22N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-MRSA agent 5 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-MRSA agent 52490154-44-2BacterialAnti-MRSA agenthERG activityInhibitorinhibitorinhibit

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产品名称：
Anti-MRSA agent 5
目录号：
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