2. Anti-infection
  3. Bacterial
  4. Antibacterial agent 127

Antibacterial agent 127 (Compound 23) 是一种有效的抗细菌 (antibacterial) 剂。

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Antibacterial agent 127 Chemical Structure

Antibacterial agent 127 Chemical Structure

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Antibacterial agent 127 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antibacterial agent 127 (Compound 23) is a potent antibacterial agent[1].

IC50 & Target

Bacterial[1]
体外研究
(In Vitro)

Antibacterial agent 127 (Compound 23) (0-64 μg/mL; 20 h) 表现出抗细菌活性，对MSSA ATCC29213、MSSA ATCC25923、MRSAb、MRSEb、E.coli ATCC25922 和 S.pullorum 的 MIC 分别为 0.063、0.063、0.063、0.25、32 和 64 μg/mL[1]。
Antibacterial agent 127 具有良好的代谢稳定性 (在大鼠肝微粒体的 t1/2 为 3.25 min)[1]。
Antibacterial agent 127 对 CYP3A4 (咪达唑仑) 和 CYP3A4 (睾酮) 有中等抑制作用，IC50 值分别为 2.64 和 1.94 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antibacterial agent 127 相关抗体:
体内研究
(In Vivo)

Antibacterial agent 127 (Compound 23) (50 mg/kg; i.p.; single dose) 在小鼠大腿感染模型中有效抑制 MRSA[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Kunming mice, neutropenic mouse thigh infection model[1]
Dosage: 50 mg/kg
Administration: Intraperitoneal injection, single dose
Result: Reduced bacteria count with a value of 1.84 log10 CFU/mL in comparison with vehicle control group.
分子量

527.68

Formula

C28H37N3O5S
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antibacterial agent 127 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antibacterial agent 127Antibacterial agent127Antibacterial agent-127BacterialMSSAMRSAbMRSEbE.coliS.pullorumInhibitorinhibitorinhibit

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产品名称：
Antibacterial agent 127
目录号：
HY-151937
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