2. Anti-infection
  3. Parasite
  4. Antimalarial agent 51

Antimalarial agent 51 (Compound 2) 是一种口服有效的抗疟疾化合物。Antimalarial agent 51 通过抑制疟原虫表面阴离子通道 (PSAC) 阻断疟原虫的营养摄取。Antimalarial agent 51 在营养受限条件下显著抑制疟原虫生长。Antimalarial agent 51 与残留转运抑制剂 PRT-2 联用可增强杀灭疟原虫的效果。Antimalarial agent 51 可用于针对 PSAC 通道疟疾的研究。

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Antimalarial agent 51 Chemical Structure

Antimalarial agent 51 Chemical Structure

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Antimalarial agent 51 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC). Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel[1].

分子量

347.41

Formula

C20H21N5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antimalarial agent 51 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antimalarial agent 51Antimalarial agent51Antimalarial agent-51ParasiteHepG2 cellsNSG mice3D7ALDHCLAG3PSACInhibitorinhibitorinhibit

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目录号：
HY-176223
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