2. Others Neuronal Signaling Membrane Transporter/Ion Channel Apoptosis Epigenetics
  3. Reference Standards TRP Channel Necroptosis Epigenetic Reader Domain
  4. Artepillin C (Standard)

Artepillin C (Standard) 

目录号: HY-N10319R 纯度: ≥98%
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Artepillin C (Standard) 是 Artepillin C (HY-N10319) 的分析标准品。本产品用于研究及分析应用。Artepillin C 是一种口服有效的 CREB/CRTC2 抑制剂和 TRPA1 共价激动剂 (EC50=1.8 μM)。Artepillin C 抑制 CREB/CRTC2 介导的基因转录，下调 BMAL1 表达以调节糖脂代谢。Artepillin C 还可以激活 TRPA1 通道诱导辛辣味觉信号。Artepillin C 可抑制肿瘤细胞增殖、诱导凋亡 (apoptosis)、改善胰岛素抵抗及抑制肝脏脂质合成。Artepillin C 可用于代谢综合征、肿瘤防治及炎症的研究。

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Artepillin C (Standard) Chemical Structure

Artepillin C (Standard) Chemical Structure

CAS No. : 72944-19-5

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生物活性

Artepillin C (Standard) is the analytical standard of Artepillin C (HY-N10319). This product is intended for research and analytical applications. Artepillin C is an orally active CREB/CRTC2 inhibitor and TRPA1 covalent agonist (EC50=1.8 μM). Artepillin C inhibits CREB/CRTC2-mediated gene transcription and downregulates BMAL1 expression to regulate glucose and lipid metabolism. Artepillin C can also activate TRPA1 channels to induce spicy taste signals. Artepillin C can inhibit tumor cell proliferation, induce apoptosis, improve insulin resistance and inhibit liver lipid synthesis. Artepillin C can be used in the study of metabolic syndrome, tumor prevention and treatment, and inflammation.

分子量

300.39

Formula

C19H24O3
CAS 号
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
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Keywords:

Artepillin C (Standard)72944-19-5Reference StandardsTRP ChannelNecroptosisEpigenetic Reader DomainTransient receptor potential channelsBile acidcholereticantitumorgastroprotectiveanti-inflammatoryantimicrobialantioxidantInhibitorinhibitorinhibit

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