2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. ATP magnesium

ATP magnesium  (Synonyms: Adenosine 5'-triphosphate magnesium)

目录号: HY-B2176E
产品使用指南 技术支持

ATP (Adenosine 5'-triphosphate) magnesium 是体内能量储存和代谢的重要物质，为代谢提供能量，同时在细胞中作为辅酶发挥作用。ATP magnesium 是免疫和炎症中重要的内源性信号分子。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

ATP magnesium Chemical Structure

ATP magnesium Chemical Structure

CAS No. : 1476-84-2

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

ATP magnesium 的其他形式现货产品:

ATP

Other Forms of ATP magnesium:

ATP magnesium 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 79 篇科研文献

WB
Cell Viability Assay
RT-PCR

    ATP magnesium purchased from MCE. Usage Cited in: Immunity. 2024 Mar 12;57(3):495-512.e11.  [Abstract]

    Representative western blots and analyses of the following proteins in BV2 cells treated with vehicle (Con), LPS (200 ng/ml, 3 h), LPS + ATP (3 mM, 30 min), or LPS + ATP-siNKAα1 (one experiment, n = 3). Supernatant (Sup) IL-1β (P17) and cellular lysates (Lys) pro-IL-1β; (I) supernatant caspase-1 (P20) and lysates pro-caspase-1.

    ATP magnesium purchased from MCE. Usage Cited in: Transl Res. 2022.

    LPS/ATP treatment significantly promotes expression of NLRP3 and production of N-GSDMD in HAEC. HAEC are pretreated with LPS (500ng/ml) for 5 h and then stimulated with ATP (5 mM) for 1 h.

    ATP magnesium purchased from MCE. Usage Cited in: Cell Death Differ. 2021 Sep 11.  [Abstract]

    Primary BMDM cells were isolated from WT and Trim21-/- C57BL/6 mice. Cells were primed with 1 μg/mL LPS for 2 h followed by 5 mM ATP or 20 μM Nig or 30 μM flagellin for 30 min. Cell viability are determined by the Cell Counting Kit-8.

    ATP magnesium purchased from MCE. Usage Cited in: Crit Care. 2021 Oct 12;25(1):356.  [Abstract]

    Stimulation of Raw264.7 macrophages with PBS/PBS-Exo/TNF-Exo for 24 h and treatment with PBS, 5 mM ATP or 20 mM nigericin for 2 h. Cleavage of GSDMD by western blot. GSDMD-FL: full-length GSDMD, GSDMD-N: N-terminal cleavage products of GSDMD.

    ATP magnesium purchased from MCE. Usage Cited in: Cell Death Dis. 2020 Feb 18;11(2):132.   [Abstract]

    KCs were transfected with lnc-Lfar1 siRNA for 24 h, followed by stimulation with 100 ng/ml LPS for 4 h and subsequently treated with 5 mM ATP or 100 ng/ml for 2 h to induce pyroptosis. a, b The protein level of NLRP3, Caspase1 and GSDMD was determined by western blot. GAPDH was used as an internal control.

    ATP magnesium purchased from MCE. Usage Cited in: Cell Death Dis. 2020 Feb 18;11(2):132.   [Abstract]

    KCs and BMMs were stimulated with 100 ng/mL LPS for 4 hours and subsequently treated them with 5 mM ATP or 100 ng/mL for 2 hours to induce pyroptosis. The RNA level of lnc-Lfar1 was determined by qRT-PCR.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation[1][2].

    体外研究
    (In Vitro)

    ATP (5 mM；1 小时) 与 LPS (1 μg/mL) 共同处理对 HGFs 中 NLRP3 炎性体的激活具有协同作用[3]。
    ATP (2 mM；0.5-24 小时) 以 caspase-1 激活依赖性方式诱导 BMDM 分泌 IL-1β、KC 和 MIP-2[4]。
    ATP 促进中性粒细胞趋化性体外[4]。

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    ATP magnesium 相关抗体:
    体内研究
    (In Vivo)

    ATP (50 mg/kg；ip) magnesium 在体内保护小鼠免受细菌感染[4]。
    ATP magnesium 在体内诱导 IL-1β、KC 和 MIP-2 的分泌以及中性粒细胞募集[4]。

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.
    Clinical Trial
    分子量

    531.49

    同用名

    Adenosine 5'-triphosphate magnesium

    Formula

    C10H16MgN5O13P3
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    ATP magnesium 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    ATP1476-84-2Adenosine 5'-triphosphateEndogenous MetaboliteenergystoragemetabolismimmunityinflammationNLRP3inflammasomecytokineInhibitorinhibitorinhibit

    您最近查看的产品:

    Your information is safe with us. * Required Fields.

       产品名称：

    		  

    * 需求量：

    * 客户姓名：

    		 

    * Email：

    * 电话：

    		 

    * 公司或机构名称：

       留言给我们：

    Bulk Inquiry

    Inquiry Information

    产品名称：
    ATP magnesium
    目录号：
    HY-B2176E
    需求量：

    Request for HNMR Report

    Please fill out this form to request the QC report. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

       产品名称：

    		  

    * Lot #：

    * 客户姓名：

    		 

    * Email：

       电话：

    		 

    * 部门：

    * 公司或机构名称：

    		 

       留言给我们：

    Request for HNMR Report

    We have received your request and will respond to you as soon as possible.

    嗨！很高兴为您提供帮助！

    尊敬的 MCE 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z