2. Immunology/Inflammation
  3. Thrombopoietin Receptor
  4. Avatrombopag hydrochloride (Standard)

Avatrombopag hydrochloride (Standard) 

目录号: HY-13463BR 纯度: ≥98%
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Avatrombopag (hydrochloride) (Standard） 是 Avatrombopag (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Avatrombopag (AKR-501) hydrochloride 是一种口服活性的非肽血小板生成素受体 (TPO receptor) 激动剂 (EC50=3.3 nM)。Avatrombopag hydrochloride 可模拟TPO 的生物活性。Avatrombopag hydrochloride 通过激活细胞内信号传导系统来增加血小板的产生，并促进造血前体细胞产生血小板和巨核细胞。Avatrombopag hydrochloride 是细胞色素 P450 (CYP) 2C9 和 CYP3A 的底物。

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Avatrombopag hydrochloride (Standard) Chemical Structure

Avatrombopag hydrochloride (Standard) Chemical Structure

CAS No. : 570403-17-7

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生物活性

Avatrombopag (hydrochloride) (Standard) is the analytical standard of Avatrombopag (hydrochloride). This product is intended for research and analytical applications. Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A.

分子量

686.12

Formula

C29H35Cl3N6O3S2
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Avatrombopag hydrochloride (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Avatrombopag hydrochloride (Standard)570403-17-7Thrombopoietin ReceptormimicTPOmegakaryocytopoiesismegakaryocytesphosphorylationproliferationNOD/SCIDInhibitorinhibitorinhibit

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