1. Apoptosis
  2. Apoptosis
  3. Bursehernin

Bursehernin  (Synonyms: Methylpluviatolide)

目录号: HY-N10670
产品使用指南

Bursehernin (Methylpluviatolide) 是一种抗肿瘤剂。Bursehernin 诱导细胞凋亡 (Apoptosis) 和细胞周期停滞在 G2/M 期。Bursehernin 具有抗增殖活性。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Bursehernin Chemical Structure

Bursehernin Chemical Structure

CAS No. : 40456-51-7

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bursehernin (Methylpluviatolide) is an antitumor agent. Bursehernin induces Apoptosis and cell cycle arrest at G2/M phase. Bursehernin shows anti-proliferative activity[1][2].

体外研究
(In Vitro)

Bursehernin (4.3 µM for MCF-7 cells, 3.7 µM for KKU-M213 cells; 4, 48, 72 h) 以时间依赖的方式诱导细胞凋亡和细胞周期停滞在G2/M期 [1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay [1]

Cell Line: MCF-7, MDA-MB-468, MDA-MB-231, HT-29, KKU-M213, KKU-K100, KKU-M055, L-929, MMNK-1 cells
Concentration: 0-100 µM
Incubation Time: 72 h
Result: Showed anti-proliferative activity with IC50s of 11.96, 8.24, 14.26, 47.53, 3.70, 12.38, 17.38, 26.36, 7.45 µM for MCF-7, MDA-MB-468, MDA-MB-231, HT-29, KKU-M213, KKU-K100, KKU-M055, L-929, MMNK-1 cells, respectively.

Cell Cycle Analysis [1]

Cell Line: MCF-7, KKU-M213 cells
Concentration: 4.3 µM for MCF-7 cells, 3.7 µM for KKU-M213 cells
Incubation Time: 24, 48, 72 h
Result: Induced cell cycle arrest at G2/M phase.

Western Blot Analysis [1]

Cell Line: MCF-7, KKU-M213 cells
Concentration: 4.3 µM for MCF-7 cells, 3.7 µM for KKU-M213 cells
Incubation Time: 24, 48, 72 h
Result: Decreased the expression of topoisomerase II, STAT 3, cyclin D1, and p21.

Apoptosis Analysis [1]

Cell Line: MCF-7 cells
Concentration: 0, 2.15, 4.30, 8.60 µM
Incubation Time: 24, 48, 72, 96 h
Result: Induced apoptosis in a time- and dose-dependent manner.
分子量

370.40

Formula

C21H22O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Bursehernin
目录号:
HY-N10670
需求量: