2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. c-Fms-IN-9

c-Fms-IN-9 是一种 c-FMS 抑制剂，详细信息请参考专利文献 WO2014145023A1 中的化合物 Example 7。c-Fms-IN-9 抑制非磷酸化的 c-FMS 激酶 (uFMS) 和 uKIT，IC50 分别为 <0.01 μM 和 0.1-1 μM。

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c-Fms-IN-9 Chemical Structure

c-Fms-IN-9 Chemical Structure

CAS No. : 1628574-50-4

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c-Fms-IN-9 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

IC50 & Target

c-FMS[1]
体外研究
(In Vitro)

c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

c-Fms-IN-9 相关抗体:
分子量

405.45

Formula

C21H23N7O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

c-Fms-IN-9 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

c-Fms-IN-91628574-50-4c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RInhibitorinhibitorinhibit

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