1. Apoptosis
  2. Caspase
  3. c9,t11,c15-CLNA

c9,t11,c15-CLNA 是一种由植物乳杆菌 ZS2058 产生的共轭亚麻酸 (CLNA) 异构体。c9,t11,c15-CLNA 具有显著的抗结肠癌细胞增殖活性 (IC50: 18.26 μM)。c9,t11,c15-CLNA 通过激活 caspase-1 介导的经典焦亡途径,诱导细胞焦亡 (pyroptosis)。c9,t11,c15-CLNA 能够用于结肠癌的研究。

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c9,t11,c15-CLNA Chemical Structure

c9,t11,c15-CLNA Chemical Structure

CAS No. : 15909-18-9

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  • 生物活性

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  • 参考文献

生物活性

c9,t11,c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. c9,t11,c15-CLNA has significant anti-proliferation activity against colon cancer cells (IC50: 18.26 μM). c9,t11,c15-CLNA induces pyroptosis by activating the canonical pyroptosis pathway mediated by caspase-1. c9,t11,c15-CLNA can be used in the study of colon cancer[1].

分子量

278.43

Formula

C18H30O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

c9,t11,c15-CLNA 相关分类

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
c9,t11,c15-CLNA
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HY-171837
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