1. Cell Cycle/DNA Damage Epigenetics
  2. Sirtuin
  3. CL5D

CL5D 是一种蛋白去乙酰化酶 SIRT6 激活剂。CL5D 能够显著增强 SIRT6 的脱乙酰化活性,提高催化效率。CL5D 通过促进 SIRT6 的构象变化来调节其活性,尤其依赖 Arg-65 残基的作用。CL5D 可用于研究 SIRT6 的激活机制及其在代谢、DNA 修复和衰老中的功能。

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CL5D Chemical Structure

CL5D Chemical Structure

CAS No. : 2488745-53-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CL5D is an activator of protein deacetylase SIRT6. CL5D can significantly enhance the deacetylation activity of SIRT6 and improve its catalytic efficiency. CL5D regulates SIRT6 activity by promoting conformational changes, especially dependent on the role of Arg-65 residue. CL5D can be used to study the activation mechanism of SIRT6 and its function in metabolism, DNA repair and aging[1].

分子量

731.58

Formula

C29H11Cl7N2O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CL5D
目录号:
HY-169846
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