2. Cell Cycle/DNA Damage
  3. CDK
  4. Cyclin K degrader 1

Cyclin K degrader 1（化合物 40）是一种基于 AT7519（HY-50940）的 Cyclin K 降解剂，DC[50]为 21 nM。

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Cyclin K degrader 1 Chemical Structure

Cyclin K degrader 1 Chemical Structure

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Cyclin K degrader 1 相关抗体

Top Publications Citing Use of Products

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CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclin K degrader 1 (compound 40) is an AT7519 (HY-50940) based Cyclin K degrader with DC50 of 21 nM[1].

体外研究
(In Vitro)

Cyclin K degrader 1（1 μM, 2 h）在有 DDB-1 参与的情况下降解 Cyclin K[1]。
Cyclin K degrader 1（1 μM, 2 h）能够降解 99 ± 1 % Cyclin K，DC50值是 21 nM, Dmax >95%， CDK12 Kd值为 1000 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cyclin K degrader 1 相关抗体:
分子量

466.32

Formula

C23H17Cl2N5O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cyclin K degrader 1 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

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Keywords:

Cyclin K degrader 1Cyclin K degrader1Cyclin K degrader-1CDKCyclin dependent kinaseCDK12Cyclin KHEK293TInhibitorinhibitorinhibit

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产品名称：
Cyclin K degrader 1
目录号：
HY-161168
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