2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Cyclochlorotine

Cyclochlorotine 是一种霉菌毒素，可从黄变米感染源 Penicillium islandicum Sopp 中提取得到。Cyclochlorotine 促进糖原分解，抑制糖原合成，在肝细胞中影响脂肪合成和蛋白质合成。Cyclochlorotine 在肝脏中表现出慢性毒性，在小鼠模型中诱发肝纤维化和肝硬化。Cyclochlorotine 表现出致癌性。

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Custom Peptide Synthesis

Cyclochlorotine Chemical Structure

Cyclochlorotine Chemical Structure

CAS No. : 12663-46-6

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Cyclochlorotine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclochlorotine is a mycotoxin that can be extracted from the yellow rice infectant Penicillium islandicum Sopp. Cyclochlorotine promotes glycogenolysis, inhibits glycogen synthesis, affects fat synthesis and protein synthesis in liver cells. Cyclochlorotine exhibits chronic toxicity in liver that induces liver fibrosis and cirrhosis in mouse models. Cyclochlorotine exhibits carcinogenicity[1].

分子量

572.44

Formula

C24H31Cl2N5O7
CAS 号
结构分类
初始来源

Penicillium islandicum
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cyclochlorotine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclochlorotine12663-46-6Endogenous MetaboliteInhibitorinhibitorinhibit

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