2. Others Autophagy Vitamin D Related/Nuclear Receptor Anti-infection Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Complement System Antibiotic Autophagy Glucocorticoid Receptor Mitophagy ADC Cytotoxin Isotope-Labeled Compounds Bacterial SARS-CoV
  4. Dexamethasone acetate-d5

Dexamethasone acetate-d5  (Synonyms: Dexamethasone 21-acetate-d5; Hexadecadrol acetate-d5)

目录号: HY-W744577
产品使用指南 技术支持

Dexamethasone acetate-d5 (Dexamethasone 21-acetate-d5; Hexadecadrol acetate-d5) 是 Dexamethasone acetate (HY-14648A) 的氘代物。Dexamethasone acetate (Dexamethasone 21-acetate) 是一种糖皮质激素受体 (glucocorticoid receptor) 激动剂。Dexamethasone 还显着降低中性粒细胞的 CD11b，CD18 和 CD62L 表达，以及单核细胞的 CD11b 和 CD18 表达。Dexamethasone 有潜力用于 COVID-19 的研究。Dexamethasone 在 LPS 诱导的巨噬细胞炎症反应中，抑制含有炎性 miRNA-155 的外泌体的产生。

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Dexamethasone acetate-d<sub>5</sub> Chemical Structure

Dexamethasone acetate-d5 Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥6000
3 - 4 周
5 mg 现货 3 - 4 周
10 mg   询价  
50 mg   询价  

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Customer Review

Other Forms of Dexamethasone acetate-d5:

Dexamethasone acetate-d5 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Dexamethasone acetate-d5 (Dexamethasone 21-acetate-d5; Hexadecadrol acetate-d5) is the deuterium labeled Dexamethasone acetate (HY-14648A). Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dexamethasone acetate-d5 相关抗体:
分子量

439.53

Formula

C24H26D5FO6
非标记 CAS
中文名称

醋酸地塞美松-d5；醋酸氟美松-d5；醋酸地塞米松-d5；地塞米松醋酸酯-d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Dexamethasone acetate-d5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dexamethasone acetate-d5Dexamethasone 21-acetate-d5 Hexadecadrol acetate-d5醋酸地塞美松-d5醋酸氟美松-d5醋酸地塞米松-d5地塞米松醋酸酯-d5Complement SystemAntibioticAutophagyGlucocorticoid ReceptorMitophagyADC CytotoxinIsotope-Labeled CompoundsBacterialSARS-CoVMitochondrial AutophagyADC PayloadSARS coronavirusInhibitorinhibitorinhibit

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