2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. Dichlorphenamide disodium

Dichlorphenamide disodium  (Synonyms: Diclofenamide disodium)

目录号: HY-B0397A
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Dichlorphenamide (Diclofenamide) disodium 是一种具有口服活性的，特异性，碳酸酐酶 (carbonic anhydrase) 抑制剂，可以通过抑制眼睛中水的分泌，从而降低眼压，可用于青光眼的研究。

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Dichlorphenamide disodium Chemical Structure

Dichlorphenamide disodium Chemical Structure

CAS No. : 76382-13-3

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Dichlorphenamide disodium 的其他形式现货产品:

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Dichlorphenamide disodium 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Dichlorphenamide (Diclofenamide) disodium is an orally active, specific, carbonic anhydrase inhibitor. Dichlorphenamide can reduce intraocular pressure by inhibiting the secretion of water from the eye. Dichlorphenamide can be used for glaucoma research[1].

体内研究
(In Vivo)

Dichlorphenamide disodium can reduce IOP locally in male albino rabbits[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male albino rabbits (approximately 2.5 kg)[1]
Dosage: 50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg
Administration: Eye drop of 50 μL or oral gavage of 2 mg/kg or 6 mg/kg，5 hours
Result: Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration. And demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
Clinical Trial
分子量

351.14

Formula

C6H6Cl2N2Na2O4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dichlorphenamide disodium 相关分类

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Keywords:

Dichlorphenamide disodium76382-13-3Diclofenamide disodiumCarbonic AnhydraseCarbonate dehydrataseCarbonic anhydrase inhibitorGlaucomaEyesInhibitorinhibitorinhibit

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