1. Cytoskeleton
  2. Dynamin
  3. Dynamin IN-2

Dynamin IN-2 (compound 43),一种Wiskostatin (HY-12534) 类似物,是一种有效的 dynamin 抑制剂,对 dynamin I GTPaseIC50 为 1.0 μM。Dynamin IN-2 还可阻断网格蛋白介导的内吞作用 (CME),IC50 为 9.5 μM。

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Dynamin IN-2 Chemical Structure

Dynamin IN-2 Chemical Structure

CAS No. : 1345853-49-7

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规格 价格 是否有货 数量
1 mg ¥3969
1 周
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1].

IC50 & Target

IC50: 1.0 ± 0.2 μM (dyn I GTPase), 9.5 ± 2.5 μM (CME)[1]

分子量

364.87

Formula

C22H21ClN2O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Dynamin IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dynamin IN-2
目录号:
HY-152216
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