2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. Toll-like Receptor (TLR) Stearoyl-CoA Desaturase (SCD)
  4. E6446 dihydrochloride (Standard)

E6446 dihydrochloride (Standard) 

目录号: HY-12756AR 纯度: ≥98%
产品使用指南 技术支持

E6446 (dihydrochloride) (Standard） 是 E6446 (dihydrochloride) 的分析标准品。本产品用于研究及分析应用。E6446 dihydrochloride 是一种有效的、可口服的 TLR7 和 TLR9 拮抗剂，可用于有害炎症反应的研究。E6446 dihydrochloride 还是强效的 SCD1 抑制剂 (KD: 4.61 μM)，通过 SCD1-ATF3 信号传导显着抑制脂肪形成分化和肝脂肪生成。E6446 dihydrochloride 还改善高脂饮食 (HFD) 喂养小鼠的肝脏病变，可用于非酒精性脂肪肝病 (NAFLD) 的研究。

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E6446 dihydrochloride (Standard) Chemical Structure

E6446 dihydrochloride (Standard) Chemical Structure

CAS No. : 1345675-25-3

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  • 产品信息

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生物活性
分子量

522.51

Formula

C27H37Cl2N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

E6446 dihydrochloride (Standard) 相关分类

  • 摩尔计算器

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E6446 dihydrochloride (Standard)1345675-25-3Toll-like Receptor (TLR)Stearoyl-CoA Desaturase (SCD)high-fat dietnon-alcoholic fatty liver diseaseNAFLDadipogenic differentiationhepatic lipogenesisInhibitorinhibitorinhibit

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