2. Apoptosis
  3. MDM-2/p53 Apoptosis Ferroptosis
  4. Eprenetapopt

Eprenetapopt  (Synonyms: APR-246; PRIMA-1Met)

目录号: HY-19980G
产品使用指南 技术支持

Eprenetapopt (GMP) (APR-246(GMP)) 是 GMP 级的 Eprenetapopt (HY-19980)。Eprenetapopt (APR-246) 是同类首创的小分子，可恢复 TP53 突变细胞中的野生型 p53 功能。Eprenetapopt 可引发肿瘤细胞凋亡。Eprenetapopt 还靶向硒蛋白硫氧还蛋白还原酶 1 (TrxR1)，它是细胞氧化还原平衡的关键调节因子。

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Eprenetapopt Chemical Structure

Eprenetapopt Chemical Structure

CAS No. : 5291-32-7

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Eprenetapopt 相关抗体

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  • 生物活性

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生物活性

Eprenetapopt (GMP) (APR-246(GMP)) is Eprenetapopt (HY-19980) in GMP grade. Eprenetapopt (APR-246) is a first-in-class, small molecule that restores wild-type p53 functions in TP53-mutant cells. Eprenetapopt triggers apoptosis in tumor cells. Eprenetapopt also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance[1][2][3].

分子量

199.25

Formula

C10H17NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Eprenetapopt 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Eprenetapopt (GMP)5291-32-7APR-246 (GMP)PRIMA-1Met (GMP)MDM-2/p53ApoptosisFerroptosisp53apoptosiswild-type p53TP53-mutantthioredoxin reductase 1 (TrxR1)Inhibitorinhibitorinhibit

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